"Well, I know there's someone out there who can create universes and I know there are several that can destroy them. There's the handful of immortals wandering between universes refusing to talk to anyone. We've found artifacts that suggest, sometimes explicitly say, that the beings who invented them have gone post-physical. Some worlds have arbitrarily large sources of magical power, that usually are limited to natives or have complex rules that make them difficult to use."
no subject